The supplement library
Every supplement gets the same treatment: what it does, the evidence grade, the worth-it grade, dosage context, and what the experts agree on. Supplements only, never brands. The library keeps growing.
Performance
Creatine
The most studied sports supplement in the world, graded.
Sleep and Recovery
Magnesium
Essential mineral, noisy marketing. Here is what the trials say.
Foundational
Vitamin D
The deficiency is common. The hype is louder than the data.
Metabolic
AKG (Alpha-Ketoglutarate)
One small aging trial made it famous. The replication has not arrived.
Heart
Omega-3 (EPA/DHA)
Great for triglycerides. The rest is still being argued.
Stress
Ashwagandha
The adaptogen with the most trials, and the most caveats.
Metabolic
Berberine
Called nature's metformin. The trials are smaller than the nickname.
Skin and Joints
Collagen Peptides
Modest skin benefits, premium price. Do the math.
Foundational
Zinc
Cheap, essential, and easy to overdo.
Heart
CoQ10
The statin companion with a thin trial record.
Metabolic
Taurine
Big mouse study, tiny human record.
Sleep and Recovery
Glycine
The quiet amino acid in your sleep stack.
Metabolic
NMN
The biomarker moves. The outcomes have not.
Heart
Vitamin K2
Vitamin D's running mate, still proving itself.
Performance
Electrolytes
Essential for athletes. Expensive salt water for everyone else.
Metabolic
Urolithin A
The pomegranate metabolite with real human trials.
Metabolic
Spermidine
The longevity molecule from epidemiology, still waiting on trials.
Peptides (research)
BPC-157
Famous in gyms, absent from human trials.
Peptides (research)
TB-500
The other healing peptide with no human trials.
Peptides (research)
GHK-Cu
The skin peptide with small human studies.
Peptides (research)
CJC-1295 / Ipamorelin
Growth hormone secretagogues with thin human data.
Sleep and Recovery
L-Theanine
Calm focus in a capsule, best known next to caffeine.
Sleep and Recovery
Apigenin
The chamomile compound in Huberman's sleep stack.
Metabolic
Sulforaphane
Rhonda Patrick's signature molecule, from broccoli sprouts.
Sleep and Recovery
Melatonin
The most studied sleep aid, usually overdosed.
Metabolic
NAC
The glutathione precursor hospitals actually use.
Metabolic
Resveratrol
The red-wine molecule that launched a thousand headlines.
Metabolic
Fisetin
The senolytic candidate from strawberries.
Metabolic
Quercetin
Fisetin's older cousin in the senolytic conversation.
Prescription
Rapamycin
The most exciting and most serious molecule in longevity.
Prescription
Metformin
The diabetes drug auditioning for a second career.
Cognitive
Lion's Mane
The mushroom of focus, with small trials behind it.
Cognitive
Rhodiola
The arctic adaptogen for fatigue.
Performance
Tongkat Ali
Southeast Asian root extract marketed for testosterone and male vitality
Performance
Fadogia
Nigerian shrub with animal-only testosterone claims and real toxicity signals
Performance
Shilajit
Himalayan mineral resin with one positive testosterone trial and real contamination risk
Performance
Cordyceps
Endurance mushroom with the best exercise evidence of any medicinal fungus
Cognitive
Bacopa
Ayurvedic memory herb with a consistent but slow-acting signal
Cognitive
Ginkgo
The classic memory herb whose best evidence is modest and dementia-specific
Cognitive
Phosphatidylserine
Brain phospholipid with an inconsistent memory signal and a high price
Cognitive
Acetyl-L-Carnitine
Mitochondrial nutrient with real depression and fatigue trial data
Cognitive
PQQ
Mitochondrial antioxidant with small trials and manufacturer-linked research
Metabolic
Alpha-Lipoic Acid
Antioxidant with the strongest supplement evidence in diabetic neuropathy
Metabolic
Probiotics
Live microbes with strong strain-specific evidence and weak generic claims
Metabolic
Prebiotics
Fermentable fibers that feed your own beneficial gut bacteria
Metabolic
Butyrate
Key gut metabolite with a supplement delivery problem
Foundational
Multivitamin
A daily blend of vitamins and minerals meant to cover dietary gaps.
Performance
Whey Protein
Fast-digesting dairy protein, rich in leucine, for muscle support.
Cognitive
Caffeine
The stimulant that sharpens alertness by blocking adenosine.
Foundational
Glutathione
The body's master antioxidant, but poorly absorbed as a plain pill.
Peptides (research)
Tesamorelin
A prescription growth-hormone peptide for HIV belly fat, used off-label for aging.
Peptides (research)
Epithalon
A research tetrapeptide studied for telomerase and melatonin effects.
Peptides (research)
MOTS-c
A mitochondria-encoded peptide with interesting animal metabolic data.
Metabolic
NR (Nicotinamide Riboside)
A vitamin B3 form that reliably raises NAD+ in human blood.
Sleep and Recovery
GABA
The calm neurotransmitter in Huberman's sleep stack.
Sleep and Recovery
Ornithine
The urea-cycle amino acid with small sleep trials.
Metabolic
Betaine HCl
Supplemental stomach acid for the low-acid theory.
Foundational
Niacinamide
Vitamin B3: the cheap NAD+ precursor.
Sleep and Recovery
CBD
The cannabis compound without the high.
Foundational
Colostrum
First milk, sold for gut and immune support.
Foundational
Vitamin A
Essential, and toxic in excess.
Foundational
Biotin
The hair-skin-nails B vitamin.
Foundational
Vitamin B6
Useful at RDA levels, risky megadosed.
Foundational
Krill Oil
Omega-3s with astaxanthin, at a premium.
Metabolic
Psyllium Husk
Fiber with actual RCTs behind it.
Metabolic
Citrus Bergamot
The citrus extract with small lipid trials.
Foundational
Greens Powder
Vegetables, dehydrated and marked up.
Foundational
Desiccated Liver
The bodybuilder's multivitamin.
Prescription
Tesofensine
The once-promising obesity pill stuck in regulatory limbo.
Prescription
Semaglutide
The GLP-1 that changed obesity medicine.
Prescription
Tirzepatide
Dual GIP/GLP-1: the current efficacy leader.
Prescription
Retatrutide
Triple agonist: the pipeline's biggest number.
Foundational
Curcumin
Turmeric's active compound. Strongest case is joint pain; everything else is promising but thinner.
Performance
Beta-Alanine
The tingling amino acid with meta-analytic backing for hard efforts.
Metabolic
Beetroot Extract (Dietary Nitrate)
The vegetable nitrate with real blood pressure trials.
Metabolic
Aged Garlic Extract
Odorless garlic with genuine hypertension trials.
Metabolic
Cocoa Flavanols
The chocolate compound behind the 21,000-person COSMOS trial.
Metabolic
Plant Sterols and Stanols
The best-validated non-drug LDL intervention.
Metabolic
Ginger Extract
Dirt-cheap root with real glucose and inflammation trials.
Showing 79 of 79 ingredients.
Grades are our editorial assessment under the published methodology, reviewed and updated as new evidence lands.