Supplement
Lion's Mane
The mushroom of focus, with small trials behind it.
Lion's mane is an edible mushroom containing hericenones and erinacines, compounds that stimulate nerve growth factor (NGF) in animal models. We grade Lion's Mane C on evidence and C for worth-it at about $15-25 per month.
Evidence
Worth it
Typical cost: $15-25/month
What it does
Lion's mane is an edible mushroom containing hericenones and erinacines, compounds that stimulate nerve growth factor (NGF) in animal models. It is sold as powder or extract for focus and cognition.
What the research says
May support cognitive measures
Evidence: emerging. Small human trials show signals; needs larger replication.
DRAFT: interesting mechanism with small-trial signals; not yet convincing.
Is it worth it?
DRAFT: moderate cost for early-stage evidence.
Typical cost
$15-25/month
Common form, not a brand recommendation
Dosage contextemerging
500 to 3,000 mg per day across trials; extracts vary widely.
Safety notes
Generally well tolerated. People with mushroom allergies should avoid it. Talk to your doctor. This page is information, not medical advice.
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Lion's Mane news, graded when it happens.
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Changelog
Last updated 2026-10-15
- 2026-10-15|Batch 1 expansion entry, DRAFT. Grades provisional; expert positions unsourced unless noted.
- 2026-10-15|Goals/dosage added; prescription flag set where applicable.