Longevity Lab ReportBeta
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Supplement

CoQ10

The statin companion with a thin trial record.

Coenzyme Q10 is a compound the body makes that helps mitochondria produce energy. We grade CoQ10 C+ on evidence and C for worth-it at about $15-25 per month.

C+

Evidence

C

Worth it

Typical cost: $15-25/month

What it does

Coenzyme Q10 is a compound the body makes that helps mitochondria produce energy. Levels decline with age, and statins lower them further, which is the rationale for supplementing.

What the research says

  • May reduce statin-associated muscle symptoms

    Evidence: emerging. Small trials are mixed; some show benefit, others none. Needs verification.

  • May support heart failure outcomes as an adjunct

    Evidence: emerging. One notable trial suggested benefit; not replicated at scale. Needs verification.

DRAFT: plausible and low-risk, but the trial record is thin and mixed.

What the experts say

Every position links to its source. We include skeptics alongside supporters.

  • David Sinclair

    Source, 2026-08-27 Takes CoQ10 every night (stated in a 2020 tweet; dosage not specified).

  • Rhonda Patrick

    “Ubiquinol is another one I'm supplementing with. I'm supplementing with a pretty high dose. 200 milligrams a day.”

    Source Supplements with 200 mg/day of ubiquinol (the reduced form of CoQ10), citing randomized trials on heart and possibly brain function.

  • Bryan Johnson

    Source, 2026-03-24 Takes 100 mg of CoQ10 each morning to support energy and endurance during workouts.

Is it worth it?

C

DRAFT: moderate cost for evidence that has not yet delivered a clear win.

Typical cost

$15-25/month

Common form, not a brand recommendation

Dosage contextemerging

100 to 200 mg per day in most trials.

Safety notes

Generally well tolerated. May lower blood pressure slightly and can interact with warfarin; anyone on anticoagulants should talk to their doctor. This page is information, not medical advice.

Longevity Lab Report

CoQ10 news, graded when it happens.

New studies, dose debates, and expert shifts on coq10, in one email a week. Free.

Changelog

Last updated 2026-10-15

  • 2026-10-15|Seed entry created as DRAFT. Claims need verification against primary trials.
  • 2026-10-15|Dosage context added.
  • 2026-10-15|Goal tags added for the stack builder.