Supplement
Fisetin
The senolytic candidate from strawberries.
Fisetin is a flavonoid in strawberries and apples. We grade Fisetin C- on evidence and C for worth-it at about $20-30 per month.
Evidence
Worth it
Typical cost: $20-30/month
What it does
Fisetin is a flavonoid in strawberries and apples. In animal studies it clears senescent 'zombie' cells, which made it a leading senolytic candidate; human trials are underway but not yet decisive.
What the research says
Clears senescent cells in animals
Evidence: moderate. Mouse data is genuinely interesting; human data pending.
Extends human healthspan
Evidence: weak. No human outcomes data exists.
No published human RCT results yet
Evidence: weak. Senolytic promise rests on animal work; Mayo Clinic AFFIRM-line trials are the ones to watch. Nothing published as of this writing.
DRAFT: compelling animal story, zero human outcomes; a watchlist entry.
Is it worth it?
DRAFT: moderate cost for animal data and a plausible mechanism.
Typical cost
$20-30/month
Common form, not a brand recommendation
Dosage contextemerging
No established human dosage; small trials used varied protocols.
Safety notes
Human safety data is limited to short trials. Talk to your doctor before supplementing. This page is information, not medical advice.
Longevity Lab Report
Fisetin news, graded when it happens.
New studies, dose debates, and expert shifts on fisetin, in one email a week. Free.
Changelog
Last updated 2026-10-15
- 2026-10-15|Batch 1 expansion entry, DRAFT. Grades provisional; expert positions unsourced unless noted.
- 2026-10-15|Goals/dosage added; prescription flag set where applicable.
- 2026-10-15|Second pass: confirmed no published human RCT results; grade unchanged (C-).