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Supplement

Vitamin K2

Vitamin D's running mate, still proving itself.

Vitamin K2 (usually the MK-7 form) helps direct calcium into bone and away from soft tissue, working alongside vitamin D. We grade Vitamin K2 C+ on evidence and C+ for worth-it at about $10-15 per month.

C+

Evidence

C+

Worth it

Typical cost: $10-15/month

What it does

Vitamin K2 (usually the MK-7 form) helps direct calcium into bone and away from soft tissue, working alongside vitamin D. It is found in fermented foods like natto and in some animal products.

What the research says

  • Supports bone health in combination with vitamin D and calcium

    Evidence: moderate. Trials of MK-7 show bone marker improvements; fracture outcomes are less established. Needs verification.

  • May slow vascular calcification

    Evidence: emerging. Mechanistically plausible and early data is interesting; not proven. Needs verification.

DRAFT: sensible biology with early human data; waiting on harder outcomes.

Is it worth it?

C+

DRAFT: inexpensive with plausible upside; the evidence has not caught up to the pairing hype.

Typical cost

$10-15/month

Common form, not a brand recommendation

Dosage contextemerging

100 to 200 mcg of MK-7 per day in most trials.

Safety notes

Do not take vitamin K2 if you use warfarin or other vitamin K antagonist blood thinners unless your doctor approves; it can reduce their effect. Otherwise well tolerated at typical doses. This page is information, not medical advice.

Longevity Lab Report

Vitamin K2 news, graded when it happens.

New studies, dose debates, and expert shifts on vitamin k2, in one email a week. Free.

Changelog

Last updated 2026-10-15

  • 2026-10-15|Seed entry created as DRAFT. Warfarin interaction flagged in safety notes.
  • 2026-10-15|Dosage context added.
  • 2026-10-15|Goal tags added for the stack builder.