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Supplement

GHK-Cu

The skin peptide with small human studies.

GHK-Cu is a copper-binding peptide found naturally in human plasma, declining with age. We grade GHK-Cu C- on evidence and C for worth-it at about $20-40 per month.

C-

Evidence

C

Worth it

Typical cost: $20-40/month

What it does

GHK-Cu is a copper-binding peptide found naturally in human plasma, declining with age. It appears in cosmetic serums and is studied for skin remodeling. A few small human studies exist on skin measures. It is not an approved drug, and injectable products sold online are unregulated.

What the research says

  • May improve skin firmness and appearance

    Evidence: emerging. Small human studies on topical use; needs larger replication.

DRAFT: a handful of small human skin studies; everything beyond skin is speculation.

Is it worth it?

C

DRAFT: moderate cost; the evidence covers a narrow cosmetic claim.

Typical cost

$20-40/month

Common form, not a brand recommendation

Dosage contextemerging

Topical cosmetic use has no standard dose; no established dosage for any other route.

Safety notes

Topical cosmetic use appears low-risk. Injectable products sold online are unregulated research chemicals. Talk to your doctor before any injectable use. This page is information, not medical advice.

Longevity Lab Report

GHK-Cu news, graded when it happens.

New studies, dose debates, and expert shifts on ghk-cu, in one email a week. Free.

Changelog

Last updated 2026-10-15

  • 2026-10-15|Peptide/longevity entry added as DRAFT with research-compound framing where applicable.
  • 2026-10-15|Dosage context added.
  • 2026-10-15|Goal tags added for the stack builder.
  • 2026-10-15|Regulatory: Feb 2026 HHS announcement moved GHK-Cu toward Category 1 (compounding-eligible with prescription). Not among the six in the July 2026 PCAC vote. Not FDA approval. Evidence grade unchanged. Source: https://www.ajmc.com/view/5-things-to-know-about-the-fda-s-peptide-reversal