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Andrew Huberman

Huberman Lab sleep stack + daily foundational

Sleep-stack items are from his published Toolkit for Sleep newsletter (primary source). Omega-3 line is from published episode notes. He stresses starting with one supplement and adding only as needed.

C

Stack score

59/100

Evidence

70

Safety

100

Cost eff.

7

Est. cost

~$77/mo

Scored with our transparent rubric: evidence depth, interaction safety, cost efficiency. How stack scoring works.

The stack, item by item

  1. Creatine
    Dose reported: 5g/day
    “[It] appears to be at least five grams per day”

    Source, 2025-09-14

    A-
  2. Magnesium
    Dose reported: 145mg magnesium threonate, nightly
    “145mg Magnesium Threonate or 200mg Magnesium Bisglycinate”

    Source, 2021

    B-
  3. Glycine
    Dose reported: 2g, 3-4 nights/week
    “3-4 nights per week I also take 2g of Glycine and 100mg GABA.”

    Source, 2021

    C+
  4. Omega-3 (EPA/DHA)
    Dose reported: 1.5-2g EPA
    “Supplementing with EPA & omega-3 if you don't consume enough fish (1.5-2g EPA) is a good idea”

    Source

    B
  5. L-Theanine
    Dose reported: 100-400mg nightly
    “100-400mg Theanine”

    Source, 2021

    B-
  6. Apigenin
    Dose reported: 50mg nightly
    “50mg Apigenin”

    Source, 2021

    C+

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Last updated recently. Educational information, not medical advice. Talk to your doctor.