Uric Acid
A byproduct of purine and fructose metabolism, in mg/dL. Optimal range: Below 5.5 mg/dL; some longevity clinicians target below 5.0.
What it measures
A byproduct of purine and fructose metabolism, in mg/dL. Best known for gout, but also a marker of metabolic dysfunction.
Why it matters
Uric acid above 5.5 to 6.0 mg/dL is associated with hypertension, kidney disease, and metabolic syndrome. Longevity clinicians target lower levels than the gout threshold.
Optimal ranges
Sourced targets, not just lab reference ranges. Lab ranges describe the population; these describe where the evidence says you want to be.
Sourcing note
This target rests on credible but thin sourcing, such as expert-opinion statements or a single review. Stronger than a heuristic, weaker than a guideline. We upgrade it as better sources land.
| Range | Context |
|---|---|
| Below 5.5 mg/dL; some longevity clinicians target below 5.0 | Longevity-oriented target below the conventional gout-risk threshold; Bryan Johnson has cited below 5 mg/dL as his target. |
How to improve it
- 1
Cut fructose, sugary drinks, and beer
- 2
Stay well hydrated
- 3
Lose excess weight
- 4
Cherries and vitamin C have modest lowering effects
Connected to
Goals
Longevity Lab Report
Move your Uric Acid, know the evidence.
New research on uric acid and what moves it, in one email a week. Free.
Educational information, not medical advice. Talk to your doctor before acting on any biomarker result.